Name

BEX2 Gene

brain expressed X-linked 2

This gene belongs to the brain expressed X-linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA-binding complex that recognizes the E-box element and promotes transcription. This gene has been found to be a tumor suppressor that is silenced in human glioma. In breast cancer cells, this gene product modulates apoptosis in response to estrogen and tamoxifen, and enhances the anti-proliferative effect of tamoxifen. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]

bex2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term bex2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

BEX2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for BEX2 from the Pathway Commons Protein-Protein Interactions dataset.