Name

BHMT Gene

betaine--homocysteine S-methyltransferase

This gene encodes a cytosolic enzyme that catalyzes the conversion of betaine and homocysteine to dimethylglycine and methionine, respectively. Defects in this gene could lead to hyperhomocyst(e)inemia, but such a defect has not yet been observed. [provided by RefSeq, Jul 2008]

BHMT2 Gene

betaine--homocysteine S-methyltransferase 2

Homocysteine is a sulfur-containing amino acid that plays a crucial role in methylation reactions. Transfer of the methyl group from betaine to homocysteine creates methionine, which donates the methyl group to methylate DNA, proteins, lipids, and other intracellular metabolites. The protein encoded by this gene is one of two methyl transferases that can catalyze the transfer of the methyl group from betaine to homocysteine. Anomalies in homocysteine metabolism have been implicated in disorders ranging from vascular disease to neural tube birth defects such as spina bifida. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010]

bhmt Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term bhmt in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

BHMT Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for BHMT from the Pathway Commons Protein-Protein Interactions dataset.

bhmt2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term bhmt2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Betaine-homocysteine S-methyltransferase, BHMT Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Betaine-homocysteine S-methyltransferase, BHMT protein domain from the InterPro Predicted Protein Domain Annotations dataset.

BHMT2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for BHMT2 from the Pathway Commons Protein-Protein Interactions dataset.