Name

BMPR1A Gene

bone morphogenetic protein receptor, type IA

The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. [provided by RefSeq, Jul 2008]

BMPR1APS1 Gene

bone morphogenetic protein receptor, type IA pseudogene 1

BMPR1APS2 Gene

bone morphogenetic protein receptor, type IA pseudogene 2

bmpr1a Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term bmpr1a in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

BMPR1A Gene Set

From KEA Substrates of Kinases

substrates of the kinase BMPR1A from the curated KEA Substrates of Kinases dataset.

BMPR1A Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for BMPR1A from the Pathway Commons Protein-Protein Interactions dataset.

bmpr1amediated Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term bmpr1amediated in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

BMPR1A_knockout_222_GSE48092 Gene Set

From GEO Signatures of Differentially Expressed Genes for Kinase Perturbations

genes differentially expressed following the BMPR1A_knockout_222_GSE48092 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.