bone morphogenetic protein receptor, type IB

This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]


BMPR1B antisense RNA 1 (head to head)

bmpr1b Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term bmpr1b in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

BMPR1B Gene Set

From KEA Substrates of Kinases

substrates of the kinase BMPR1B from the curated KEA Substrates of Kinases dataset.

BMPR1B Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for BMPR1B from the Pathway Commons Protein-Protein Interactions dataset.

BMPR1B Gene Set

From PhosphoSitePlus Substrates of Kinases

substrates of the kinase BMPR1B from the curated PhosphoSitePlus Substrates of Kinases dataset.