This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]

canx Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term canx in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

CANX Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CANX from the Pathway Commons Protein-Protein Interactions dataset.

Cd3g-Cd3e-Cd247-Canx complex Gene Set

From CORUM Protein Complexes

proteins in the Cd3g-Cd3e-Cd247-Canx complex protein complex from the CORUM Protein Complexes dataset.