Name

CASP7 Gene

caspase 7, apoptosis-related cysteine peptidase

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]

casp7 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term casp7 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

CASP7 Gene Set

From NURSA Protein-Protein Interactions

interacting proteins for CASP7 from the NURSA Protein-Protein Interactions dataset.

CASP7 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CASP7 from the Pathway Commons Protein-Protein Interactions dataset.