caspase 8 associated protein 2

This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Nov 2008]

casp8ap2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term casp8ap2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

CASP8AP2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CASP8AP2 from the Pathway Commons Protein-Protein Interactions dataset.

BL6193 (CASP8AP2) Gene Set

From NURSA Protein Complexes

proteins in the BL6193 (CASP8AP2) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.