Name

CD46 Gene

CD46 molecule, complement regulatory protein

The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010]

CD46P1 Gene

CD46 molecule, complement regulatory protein pseudogene 1

cd46 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cd46 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

CD46 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CD46 from the Pathway Commons Protein-Protein Interactions dataset.

cd46dependent Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cd46dependent in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

cd46cyt2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cd46cyt2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

cd46cyt1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cd46cyt1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

cd46h2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cd46h2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Membrane cofactor protein CD46 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Membrane cofactor protein CD46 protein domain from the InterPro Predicted Protein Domain Annotations dataset.