CDC25B Gene

cell division cycle 25B

CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist. [provided by RefSeq, Jul 2008]

CDC25B Gene Set

From DEPOD Substrates of Phosphatases

substrates of the phosphatase CDC25B from the curated DEPOD Substrates of Phosphatases dataset.

cdc25b Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cdc25b in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

CDC25B Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CDC25B from the Pathway Commons Protein-Protein Interactions dataset.