Name

CDH13 Gene

cadherin 13

This gene encodes a member of the cadherin superfamily. The encoded protein is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. The protein lacks the cytoplasmic domain characteristic of other cadherins, and so is not thought to be a cell-cell adhesion glycoprotein. This protein acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. The gene is hypermethylated in many types of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2011]

cdh13 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cdh13 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

CDH13 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CDH13 from the Pathway Commons Protein-Protein Interactions dataset.