CDKN3 Gene

cyclin-dependent kinase inhibitor 3

The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

CDKN3 Gene Set

From DEPOD Substrates of Phosphatases

substrates of the phosphatase CDKN3 from the curated DEPOD Substrates of Phosphatases dataset.

CDKN3 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CDKN3 from the Pathway Commons Protein-Protein Interactions dataset.

CDKN3 domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the CDKN3 domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.