Name

CITED4 Gene

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4

The protein encoded by this intronless gene belongs to the CITED family of transcriptional coactivators that bind to several proteins, including CREB-binding protein (CBP) and p300, via a conserved 32 aa C-terminal motif, and regulate gene transcription. This protein also interacts with transcription factor AP2 (TFAP2), and thus may function as a co-activator for TFAP2. Hypermethylation and transcriptional downregulation of this gene has been observed in oligodendroglial tumors with deletions of chromosomal arms 1p and 19q, and associated with longer recurrence-free and overall survival of patients with oligodendroglial tumors. [provided by RefSeq, Aug 2011]

cited4 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cited4 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

CITED4 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CITED4 from the Pathway Commons Protein-Protein Interactions dataset.