carboxymethylenebutenolidase homolog (Pseudomonas)
CMBL (EC 18.104.22.168) is a cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL preferentially cleaves cyclic esters, and it activates medoxomil-ester prodrugs in which the medoxomil moiety is linked to an oxygen atom (Ishizuka et al., 2010 [PubMed 20177059]).[supplied by OMIM, Apr 2010]
CMBL Gene Set
interacting proteins for CMBL from the Pathway Commons Protein-Protein Interactions dataset.