CASP2 and RIPK1 domain containing adaptor with death domain

The protein encoded by this gene is a death domain (CARD/DD)-containing protein and has been shown to induce cell apoptosis. Through its CARD domain, this protein interacts with, and thus recruits, caspase 2/ICH1 to the cell death signal transduction complex that includes tumor necrosis factor receptor 1 (TNFR1A), RIPK1/RIP kinase, and numbers of other CARD domain-containing proteins. [provided by RefSeq, Jul 2008]

cradd Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cradd in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

CRADD Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CRADD from the Pathway Commons Protein-Protein Interactions dataset.