Name

CRY1 Gene

cryptochrome circadian clock 1

This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of the related gene in mouse results in a shortened circadian cycle in complete darkness. [provided by RefSeq, Jan 2014]

cry1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cry1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

CRY1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CRY1 from the Pathway Commons Protein-Protein Interactions dataset.

Ubiquitin E3 ligase (CRY1, SKP1A, CUL1, FBXL3) Gene Set

From CORUM Protein Complexes

proteins in the Ubiquitin E3 ligase (CRY1, SKP1A, CUL1, FBXL3) protein complex from the CORUM Protein Complexes dataset.

cry1cryptochrome Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cry1cryptochrome in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.