Name

CRYZ Gene

crystallin, zeta (quinone reductase)

Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. The former class is also called phylogenetically-restricted crystallins. This gene encodes a taxon-specific crystallin protein which has NADPH-dependent quinone reductase activity distinct from other known quinone reductases. It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family. Unlike other mammalian species, in humans, lens expression is low. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One pseudogene is known to exist. [provided by RefSeq, Sep 2008]

CRYZL1 Gene

crystallin, zeta (quinone reductase)-like 1

This gene encodes a protein that has sequence similarity to zeta crystallin, also known as quinone oxidoreductase. This zeta crystallin-like protein also contains an NAD(P)H binding site. Alternatively spliced transcript variants have been observed but their full-length nature has not been completely determined. [provided by RefSeq, Jul 2008]

CRYZP1 Gene

crystallin, zeta (quinone reductase) pseudogene 1

CRYZP2 Gene

crystallin, zeta (quinone reductase) pseudogene 2

CRYZ Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CRYZ from the Pathway Commons Protein-Protein Interactions dataset.

CRYZL1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CRYZL1 from the Pathway Commons Protein-Protein Interactions dataset.