CSE1L Gene

CSE1 chromosome segregation 1-like (yeast)

Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]

CSE1L-AS1 Gene

CSE1L antisense RNA 1

cse1l Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cse1l in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

CSE1L Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CSE1L from the Pathway Commons Protein-Protein Interactions dataset.

BL1975 (CSE1L) Gene Set

From NURSA Protein Complexes

proteins in the BL1975 (CSE1L) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.