Name

CSTB Gene

cystatin B (stefin B)

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1). [provided by RefSeq, Jul 2008]

cstb Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cstb in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

CSTB Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CSTB from the Pathway Commons Protein-Protein Interactions dataset.

CSTB_KO_GDS5089_486_mouse_Cerebellum and granule neurons Gene Set

From GEO Signatures of Differentially Expressed Genes for Gene Perturbations

genes differentially expressed following the CSTB_KO_GDS5089_486_mouse_Cerebellum and granule neurons gene perturbation from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

CSTB_KO_GSE47516_132_mouse_granule neurons Gene Set

From GEO Signatures of Differentially Expressed Genes for Gene Perturbations

genes differentially expressed following the CSTB_KO_GSE47516_132_mouse_granule neurons gene perturbation from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

CSTB_KO_GSE47516_677_mouse_mouse cerebellum P7 Gene Set

From GEO Signatures of Differentially Expressed Genes for Gene Perturbations

genes differentially expressed following the CSTB_KO_GSE47516_677_mouse_mouse cerebellum P7 gene perturbation from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

CSTB_KO_GDS5090_198_mouse_Cerebellum Gene Set

From GEO Signatures of Differentially Expressed Genes for Gene Perturbations

genes differentially expressed following the CSTB_KO_GDS5090_198_mouse_Cerebellum gene perturbation from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

CSTB_KO_GDS5091_23_mouse_cerebellar granule Gene Set

From GEO Signatures of Differentially Expressed Genes for Gene Perturbations

genes differentially expressed following the CSTB_KO_GDS5091_23_mouse_cerebellar granule gene perturbation from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

CSTB_KO_GDS5089_169_mouse_Cerebrellum Gene Set

From GEO Signatures of Differentially Expressed Genes for Gene Perturbations

genes differentially expressed following the CSTB_KO_GDS5089_169_mouse_Cerebrellum gene perturbation from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

CSTB_KO_GSE47516_18_mouse_brain (P7 cerebellum, P30 cerebellum, cerebellar granule cells) Gene Set

From GEO Signatures of Differentially Expressed Genes for Gene Perturbations

genes differentially expressed following the CSTB_KO_GSE47516_18_mouse_brain (P7 cerebellum, P30 cerebellum, cerebellar granule cells) gene perturbation from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

CSTB_KO_GDS5090_199_mouse_Cerebellum Gene Set

From GEO Signatures of Differentially Expressed Genes for Gene Perturbations

genes differentially expressed following the CSTB_KO_GDS5090_199_mouse_Cerebellum gene perturbation from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

CSTB_KO_GDS5090_398_mouse_cerebella Gene Set

From GEO Signatures of Differentially Expressed Genes for Gene Perturbations

genes differentially expressed following the CSTB_KO_GDS5090_398_mouse_cerebella gene perturbation from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

CSTB_KO_GSE47516_678_mouse_mouse cerebellum at P30 Gene Set

From GEO Signatures of Differentially Expressed Genes for Gene Perturbations

genes differentially expressed following the CSTB_KO_GSE47516_678_mouse_mouse cerebellum at P30 gene perturbation from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

CSTB_KO_GDS5089_565_mouse_cerebellum and granule neurons Gene Set

From GEO Signatures of Differentially Expressed Genes for Gene Perturbations

genes differentially expressed following the CSTB_KO_GDS5089_565_mouse_cerebellum and granule neurons gene perturbation from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

CSTB_KO_GDS5090_200_mouse_Cerebellar granule cells Gene Set

From GEO Signatures of Differentially Expressed Genes for Gene Perturbations

genes differentially expressed following the CSTB_KO_GDS5090_200_mouse_Cerebellar granule cells gene perturbation from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.