Name

DCC Gene

DCC netrin 1 receptor

This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma. [provided by RefSeq, Oct 2009]

dcc Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term dcc in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

DCC Gene Set

From MSigDB Cancer Gene Co-expression Modules

co-expressed genes for DCC from the MSigDB Cancer Gene Co-expression Modules dataset.

DCC Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for DCC from the Pathway Commons Protein-Protein Interactions dataset.

CTF18-CTF8-DCC1 complex Gene Set

From CORUM Protein Complexes

proteins in the CTF18-CTF8-DCC1 complex protein complex from the CORUM Protein Complexes dataset.

CTF8-DCC1 subcomplex Gene Set

From CORUM Protein Complexes

proteins in the CTF8-DCC1 subcomplex protein complex from the CORUM Protein Complexes dataset.

CTF18-CTF8-DCC1-RFC3 complex Gene Set

From CORUM Protein Complexes

proteins in the CTF18-CTF8-DCC1-RFC3 complex protein complex from the CORUM Protein Complexes dataset.

CTF8-CTF18-DCC1 subcomplex Gene Set

From CORUM Protein Complexes

proteins in the CTF8-CTF18-DCC1 subcomplex protein complex from the CORUM Protein Complexes dataset.

dcc342 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term dcc342 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

dccnetrin1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term dccnetrin1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

dcc1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term dcc1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

dccbs Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term dccbs in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

dcccreb Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term dcccreb in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

dccubiquitinproteasome Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term dccubiquitinproteasome in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

ATPase, F0 complex, subunit C, DCCD-binding site Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the ATPase, F0 complex, subunit C, DCCD-binding site protein domain from the InterPro Predicted Protein Domain Annotations dataset.

ODA1/DCC2 family Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the ODA1/DCC2 family protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Sister chromatid cohesion protein Dcc1 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Sister chromatid cohesion protein Dcc1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DCC-2036_Ramos (RA 1) Gene Set

From LINCS Kinativ Kinase Inhibitor Bioactivity Profiles

kinases with high inhibition of kinase activity in the DCC-2036_Ramos (RA 1) chemical bioactivity profile from the Kinativ Kinase Inhibitor Bioactivity Profiles dataset.

Role of DCC in regulating apoptosis Gene Set

From Reactome Pathways

proteins participating in the Role of DCC in regulating apoptosis pathway from the Reactome Pathways dataset.

DCC mediated attractive signaling Gene Set

From Reactome Pathways

proteins participating in the DCC mediated attractive signaling pathway from the Reactome Pathways dataset.