DDC Gene

dopa decarboxylase (aromatic L-amino acid decarboxylase)

The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2011]

DDC-AS1 Gene

DDC antisense RNA 1

ddc Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term ddc in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

DDC Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for DDC from the Pathway Commons Protein-Protein Interactions dataset.

Rad9/Ddc1 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Rad9/Ddc1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.