Name

DIABLO Gene

diablo, IAP-binding mitochondrial protein

This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]

diablo Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term diablo in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

DIABLO Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for DIABLO from the Pathway Commons Protein-Protein Interactions dataset.

Smac/DIABLO-like Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Smac/DIABLO-like protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Smac/DIABLO protein Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Smac/DIABLO protein protein domain from the InterPro Predicted Protein Domain Annotations dataset.