DKC1 Gene

dyskeratosis congenita 1, dyskerin

This gene functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs). This gene is highly conserved and widely expressed, and may play additional roles in nucleo-cytoplasmic shuttling, DNA damage response, and cell adhesion. Mutations have been associated with X-linked dyskeratosis congenita. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

dkc1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term dkc1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

DKC1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for DKC1 from the Pathway Commons Protein-Protein Interactions dataset.