Name

DKC1 Gene

dyskeratosis congenita 1, dyskerin

This gene functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs). This gene is highly conserved and widely expressed, and may play additional roles in nucleo-cytoplasmic shuttling, DNA damage response, and cell adhesion. Mutations have been associated with X-linked dyskeratosis congenita. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

dkc1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term dkc1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

DKC1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for DKC1 from the Pathway Commons Protein-Protein Interactions dataset.