Name

DNAJC2 Gene

DnaJ (Hsp40) homolog, subfamily C, member 2

This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described. [provided by RefSeq, Jul 2008]

DNAJC28 Gene

DnaJ (Hsp40) homolog, subfamily C, member 28

DNAJC27 Gene

DnaJ (Hsp40) homolog, subfamily C, member 27

DNAJC25 Gene

DnaJ (Hsp40) homolog, subfamily C , member 25

DNAJC24 Gene

DnaJ (Hsp40) homolog, subfamily C, member 24

Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).[supplied by OMIM, Mar 2008]

DNAJC22 Gene

DnaJ (Hsp40) homolog, subfamily C, member 22

DNAJC21 Gene

DnaJ (Hsp40) homolog, subfamily C, member 21

DNAJC27-AS1 Gene

DNAJC27 antisense RNA 1

DNAJC25-GNG10 Gene

DNAJC25-GNG10 readthrough

This gene represents naturally-occurring mRNAs that are co-transcribed products of the neighboring DNAJC25 and GNG10 genes. These transcripts include the first exon of DNAJC25 and the last two exons of GNG10, resulting in a protein that combines the N-terminus of DNAJC25 and the C-terminus of GNG10. [provided by RefSeq, Dec 2008]

DNAJC2 Gene Set

From CHEA Transcription Factor Targets

target genes of the DNAJC2 transcription factor in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.

DNAJC2 Gene Set

From Hub Proteins Protein-Protein Interactions

interacting proteins for hub protein DNAJC2 from the curated Hub Proteins Protein-Protein Interactions dataset.

DNAJC2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for DNAJC2 from the Pathway Commons Protein-Protein Interactions dataset.

DNAJC2-21179169-NT2-HUMAN Gene Set

From CHEA Transcription Factor Binding Site Profiles

genes with transcription factor binding evidence in the DNAJC2-21179169-NT2-HUMAN transcription factor binding site profile from the CHEA Transcription Factor Binding Site Profiles dataset.

DNAJC28 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for DNAJC28 from the Pathway Commons Protein-Protein Interactions dataset.

DNAJC22 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for DNAJC22 from the Pathway Commons Protein-Protein Interactions dataset.

DNAJC21 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for DNAJC21 from the Pathway Commons Protein-Protein Interactions dataset.

DNAJC25 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for DNAJC25 from the Pathway Commons Protein-Protein Interactions dataset.