Name

EFNA1 Gene

ephrin-A1

This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin which binds to the EPHA2, EPHA4, EPHA5, EPHA6, and EPHA7 receptors. Two transcript variants that encode different isoforms were identified through sequence analysis. [provided by RefSeq, Jul 2008]

efna1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term efna1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

EFNA1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for EFNA1 from the Pathway Commons Protein-Protein Interactions dataset.