Name

EHMT1 Gene

euchromatic histone-lysine N-methyltransferase 1

The protein encoded by this gene is a histone methyltransferase that is part of the E2F6 complex, which represses transcription. The encoded protein methylates the Lys-9 position of histone H3, which tags it for transcriptional repression. This protein may be involved in the silencing of MYC- and E2F-responsive genes and therefore could play a role in the G0/G1 cell cycle transition. Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome, also known as Kleefstra syndrome). Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

EHMT1-IT1 Gene

EHMT1 intronic transcript 1

ehmt1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term ehmt1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

EHMT1 Gene Set

From NURSA Protein-Protein Interactions

interacting proteins for EHMT1 from the NURSA Protein-Protein Interactions dataset.

EHMT1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for EHMT1 from the Pathway Commons Protein-Protein Interactions dataset.