Name

EIF5 Gene

eukaryotic translation initiation factor 5

Eukaryotic translation initiation factor-5 (EIF5) interacts with the 40S initiation complex to promote hydrolysis of bound GTP with concomitant joining of the 60S ribosomal subunit to the 40S initiation complex. The resulting functional 80S ribosomal initiation complex is then active in peptidyl transfer and chain elongations (summary by Si et al., 1996 [PubMed 8663286]).[supplied by OMIM, May 2010]

EIF5AL1 Gene

eukaryotic translation initiation factor 5A-like 1

EIF5A2 Gene

eukaryotic translation initiation factor 5A2

EIF5A2P1 Gene

eukaryotic translation initiation factor 5A2 pseudogene 1

EIF5P1 Gene

eukaryotic translation initiation factor 5 pseudogene 1

EIF5B Gene

eukaryotic translation initiation factor 5B

Accurate initiation of translation in eukaryotes is complex and requires many factors, some of which are composed of multiple subunits. The process is simpler in prokaryotes which have only three initiation factors (IF1, IF2, IF3). Two of these factors are conserved in eukaryotes: the homolog of IF1 is eIF1A and the homolog of IF2 is eIF5B. This gene encodes eIF5B. Factors eIF1A and eIF5B interact on the ribosome along with other initiation factors and GTP to position the initiation methionine tRNA on the start codon of the mRNA so that translation initiates accurately. [provided by RefSeq, Jul 2008]

EIF5A Gene

eukaryotic translation initiation factor 5A

EIF5AP4 Gene

eukaryotic translation initiation factor 5A pseudogene 4

EIF5AP3 Gene

eukaryotic translation initiation factor 5A pseudogene 3

EIF5AP2 Gene

eukaryotic translation initiation factor 5A pseudogene 2

EIF5P2 Gene

eukaryotic translation initiation factor 5 pseudogene 2

eif5 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term eif5 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

EIF5 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for EIF5 from the Pathway Commons Protein-Protein Interactions dataset.

eif5a1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term eif5a1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

eif5aii Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term eif5aii in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

eif5carboxyl Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term eif5carboxyl in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

eif5ai Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term eif5ai in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

eif5a2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term eif5a2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

eif5a Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term eif5a in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

EIF5B Gene Set

From NURSA Protein-Protein Interactions

interacting proteins for EIF5B from the NURSA Protein-Protein Interactions dataset.

EIF5A2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for EIF5A2 from the Pathway Commons Protein-Protein Interactions dataset.

EIF5AL1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for EIF5AL1 from the Pathway Commons Protein-Protein Interactions dataset.

EIF5B Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for EIF5B from the Pathway Commons Protein-Protein Interactions dataset.

EIF5A Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for EIF5A from the Pathway Commons Protein-Protein Interactions dataset.

Hypusine synthesis from eIF5A-lysine Gene Set

From Reactome Pathways

proteins participating in the Hypusine synthesis from eIF5A-lysine pathway from the Reactome Pathways dataset.