Name

EOMES Gene

eomesodermin

This gene belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

EOMES Gene Set

From CHEA Transcription Factor Targets

target genes of the EOMES transcription factor in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.

eomes Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term eomes in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

EOMES Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for EOMES from the Pathway Commons Protein-Protein Interactions dataset.

EOMES-21245162-HESC-HUMAN Gene Set

From CHEA Transcription Factor Binding Site Profiles

genes with transcription factor binding evidence in the EOMES-21245162-HESC-HUMAN transcription factor binding site profile from the CHEA Transcription Factor Binding Site Profiles dataset.

EOMES-20176728-TROPHOBLAST STEM CELLS-MOUSE Gene Set

From CHEA Transcription Factor Binding Site Profiles

genes with transcription factor binding evidence in the EOMES-20176728-TROPHOBLAST STEM CELLS-MOUSE transcription factor binding site profile from the CHEA Transcription Factor Binding Site Profiles dataset.

eomesodermin Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term eomesodermin in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

EOMES_OE_GDS5077_65_human_RUES2 Gene Set

From GEO Signatures of Differentially Expressed Genes for Gene Perturbations

genes differentially expressed following the EOMES_OE_GDS5077_65_human_RUES2 gene perturbation from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

eomes_23431145_e14dot5_neocortex_lof_mouse_gpl6246_gse43387 Gene Set

From GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations

genes differentially expressed following the eomes_23431145_e14dot5_neocortex_lof_mouse_gpl6246_gse43387 transcription factor perturbation from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.