Name

EPOR Gene

erythropoietin receptor

This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]

epor Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term epor in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

EPOR Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for EPOR from the Pathway Commons Protein-Protein Interactions dataset.

EPO-EPOR complex Gene Set

From CORUM Protein Complexes

proteins in the EPO-EPOR complex protein complex from the CORUM Protein Complexes dataset.

EPOR receptor complex Gene Set

From CORUM Protein Complexes

proteins in the EPOR receptor complex protein complex from the CORUM Protein Complexes dataset.

epors Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term epors in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.