Name

ESR2 Gene

estrogen receptor 2 (ER beta)

This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. [provided by RefSeq, Jul 2008]

ESR2 Gene Set

From CHEA Transcription Factor Targets

target genes of the ESR2 transcription factor in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.

esr2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term esr2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

ESR2 Gene Set

From Hub Proteins Protein-Protein Interactions

interacting proteins for hub protein ESR2 from the curated Hub Proteins Protein-Protein Interactions dataset.

ESR2 Gene Set

From JASPAR Predicted Transcription Factor Targets

target genes of the ESR2 transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.

ESR2 Gene Set

From MotifMap Predicted Transcription Factor Targets

target genes of the ESR2 transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.

ESR2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for ESR2 from the Pathway Commons Protein-Protein Interactions dataset.

ESR2 Gene Set

From TRANSFAC Predicted Transcription Factor Targets

target genes of the ESR2 transcription factor predicted using known transcription factor binding site motifs from the TRANSFAC Predicted Transcription Factor Targets dataset.

ESR2-21235772-MCF-7-HUMAN Gene Set

From CHEA Transcription Factor Binding Site Profiles

genes with transcription factor binding evidence in the ESR2-21235772-MCF-7-HUMAN transcription factor binding site profile from the CHEA Transcription Factor Binding Site Profiles dataset.

esr2_15280152_c57bl6_mice_soleus_skeletal_muscle_lof_mouse_gpl81_gds791 Gene Set

From GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations

genes differentially expressed following the esr2_15280152_c57bl6_mice_soleus_skeletal_muscle_lof_mouse_gpl81_gds791 transcription factor perturbation from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.