Name

FANCB Gene

Fanconi anemia, complementation group B

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group B. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]

fancb Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term fancb in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

FANCB Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for FANCB from the Pathway Commons Protein-Protein Interactions dataset.

fancbrca Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term fancbrca in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

BL2670 (FANCB) Gene Set

From NURSA Protein Complexes

proteins in the BL2670 (FANCB) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

BL2671 (FANCB) Gene Set

From NURSA Protein Complexes

proteins in the BL2671 (FANCB) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.