gamma-aminobutyric acid (GABA) A receptor, delta

Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This gene encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

gabrd Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term gabrd in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

GABRD Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for GABRD from the Pathway Commons Protein-Protein Interactions dataset.