polypeptide N-acetylgalactosaminyltransferase 6

This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. The encoded protein is capable of glycosylating fibronectin peptide in vitro and is expressed in a fibroblast cell line, indicating that it may be involved in the synthesis of oncofetal fibronectin. [provided by RefSeq, Jul 2008]

GALNT6 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for GALNT6 from the Pathway Commons Protein-Protein Interactions dataset.

galnt6fibronectin Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term galnt6fibronectin in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.