Name

GCG Gene

glucagon

The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon. [provided by RefSeq, Jul 2008]

GCGR Gene

glucagon receptor

The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of non-insulin-dependent diabetes mellitus (NIDDM).[provided by RefSeq, Jan 2010]

gcg Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term gcg in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

GCG Gene Set

From Guide to Pharmacology Protein Ligands of Receptors

receptors of the GCG ligand (protein) from the curated Guide to Pharmacology Protein Ligands of Receptors dataset.

GCG Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for GCG from the Pathway Commons Protein-Protein Interactions dataset.

gcglobulin Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term gcglobulin in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

gcgc Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term gcgc in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

gcgr Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term gcgr in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

GCGR Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for GCGR from the Pathway Commons Protein-Protein Interactions dataset.