Name

GCSH Gene

glycine cleavage system protein H (aminomethyl carrier)

Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the H protein, which transfers the methylamine group of glycine from the P protein to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH). Two transcript variants, one protein-coding and the other probably not protein-coding,have been found for this gene. Also, several transcribed and non-transcribed pseudogenes of this gene exist throughout the genome.[provided by RefSeq, Jan 2010]

GCSHP2 Gene

glycine cleavage system protein H (aminomethyl carrier) pseudogene 2

GCSHP5 Gene

glycine cleavage system protein H pseudogene 5

GCSHP4 Gene

glycine cleavage system protein H (aminomethyl carrier) pseudogene 4

GCSHP3 Gene

glycine cleavage system protein H (aminomethyl carrier) pseudogene 3

GCSH Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for GCSH from the Pathway Commons Protein-Protein Interactions dataset.