Name

GDF1 Gene

growth differentiation factor 1

This gene encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site that is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in rodents suggest that this protein is involved in the establishment of left-right asymmetry in early embryogenesis and in neural development in later embryogenesis. This protein is transcribed from a bicistronic mRNA that also encodes the longevity assurance gene. Mutations in this gene are associated with several congenital cardiovascular malformations. [provided by RefSeq, Mar 2014]

GDF15 Gene

growth differentiation factor 15

Bone morphogenetic proteins (e.g., BMP9; MIM 605120) are members of the transforming growth factor-beta (see TGFB1; MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein.[supplied by OMIM, Oct 2009]

GDF11 Gene

growth differentiation factor 11

The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice and Xenopus suggest that this protein is involved in mesodermal formation and neurogenesis during embryonic development. [provided by RefSeq, Jul 2008]

GDF10 Gene

growth differentiation factor 10

The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice suggest that the protein encoded by this gene plays a role in skeletal morphogenesis. [provided by RefSeq, Jul 2008]

gdf1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term gdf1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

GDF1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for GDF1 from the Pathway Commons Protein-Protein Interactions dataset.

gdf15 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term gdf15 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

gdf11 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term gdf11 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

gdf10 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term gdf10 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

gdf15mediated Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term gdf15mediated in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

GDF11 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for GDF11 from the Pathway Commons Protein-Protein Interactions dataset.

GDF10 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for GDF10 from the Pathway Commons Protein-Protein Interactions dataset.

GDF15 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for GDF15 from the Pathway Commons Protein-Protein Interactions dataset.