Name

GGA1 Gene

golgi-associated, gamma adaptin ear containing, ARF binding protein 1

This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) protein family. Members of this family are ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

gga1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term gga1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

GGA1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for GGA1 from the Pathway Commons Protein-Protein Interactions dataset.