Name

GNA11 Gene

guanine nucleotide binding protein (G protein), alpha 11 (Gq class)

The protein encoded by this gene belongs to the family of guanine nucleotide-binding proteins (G proteins), which function as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes one of the alpha subunits (subunit alpha-11). Mutations in this gene have been associated with hypocalciuric hypercalcemia type II (HHC2) and hypocalcemia dominant 2 (HYPOC2). Patients with HHC2 and HYPOC2 exhibit decreased or increased sensitivity, respectively, to changes in extracellular calcium concentrations. [provided by RefSeq, Dec 2013]

gna11 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term gna11 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

GNA11 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for GNA11 from the Pathway Commons Protein-Protein Interactions dataset.