Name

GRB2 Gene

growth factor receptor-bound protein 2

The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

grb2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term grb2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

GRB2 Gene Set

From Hub Proteins Protein-Protein Interactions

interacting proteins for hub protein GRB2 from the curated Hub Proteins Protein-Protein Interactions dataset.

GRB2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for GRB2 from the Pathway Commons Protein-Protein Interactions dataset.

grb2 Gene Set

From Phosphosite Textmining Biological Term Annotations

proteins co-occuring with the biological term grb2 in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

grb2-egfr complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the grb2-egfr complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

grb2-sos complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the grb2-sos complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

grb2-shp-2 complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the grb2-shp-2 complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

grb2-sos complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the grb2-sos complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

grb2-egfr complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the grb2-egfr complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

grb2-shc complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the grb2-shc complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

egfr-shc-grb2-sos complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the egfr-shc-grb2-sos complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

shc-grb2-sos complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the shc-grb2-sos complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

egfr-grb2-sos complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the egfr-grb2-sos complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

BCR-ABL (p185 fusion protein)-GRB2 complex Gene Set

From CORUM Protein Complexes

proteins in the BCR-ABL (p185 fusion protein)-GRB2 complex protein complex from the CORUM Protein Complexes dataset.

ITGA6-ITGB4-SHC1-GRB2 complex Gene Set

From CORUM Protein Complexes

proteins in the ITGA6-ITGB4-SHC1-GRB2 complex protein complex from the CORUM Protein Complexes dataset.

LAT-PLC-gamma-1-p85-GRB2-SOS signaling complex, C305 activated Gene Set

From CORUM Protein Complexes

proteins in the LAT-PLC-gamma-1-p85-GRB2-SOS signaling complex, C305 activated protein complex from the CORUM Protein Complexes dataset.

LAT-PLC-gamma-1-p85-GRB2-CBL-VAV-SLP-76 signaling complex, C305 activated Gene Set

From CORUM Protein Complexes

proteins in the LAT-PLC-gamma-1-p85-GRB2-CBL-VAV-SLP-76 signaling complex, C305 activated protein complex from the CORUM Protein Complexes dataset.

Cbl-SLP-76-Grb2 complex, Fc receptor gamma-R1 stimulated Gene Set

From CORUM Protein Complexes

proteins in the Cbl-SLP-76-Grb2 complex, Fc receptor gamma-R1 stimulated protein complex from the CORUM Protein Complexes dataset.

Frs2-Grb2-Shp2 complex, FGF stimulated Gene Set

From CORUM Protein Complexes

proteins in the Frs2-Grb2-Shp2 complex, FGF stimulated protein complex from the CORUM Protein Complexes dataset.

Shc-Grb2-mSos1 complex, EGF stimulated Gene Set

From CORUM Protein Complexes

proteins in the Shc-Grb2-mSos1 complex, EGF stimulated protein complex from the CORUM Protein Complexes dataset.

CIN85 complex (CIN85, CRK, BCAR1, CBL, PIK3R1, GRB2, SOS1) Gene Set

From CORUM Protein Complexes

proteins in the CIN85 complex (CIN85, CRK, BCAR1, CBL, PIK3R1, GRB2, SOS1) protein complex from the CORUM Protein Complexes dataset.

GRB2-SHP-2 complex, PDGF stimulated Gene Set

From CORUM Protein Complexes

proteins in the GRB2-SHP-2 complex, PDGF stimulated protein complex from the CORUM Protein Complexes dataset.

BCR-ABL (p210 fusion protein)-GRB2 complex Gene Set

From CORUM Protein Complexes

proteins in the BCR-ABL (p210 fusion protein)-GRB2 complex protein complex from the CORUM Protein Complexes dataset.

LAT-GRB2 complex, Fyn-mLck(KA) or Syk kinase activated Gene Set

From CORUM Protein Complexes

proteins in the LAT-GRB2 complex, Fyn-mLck(KA) or Syk kinase activated protein complex from the CORUM Protein Complexes dataset.

Egfr-Grb2-mSos1 complex, EGF stimulated Gene Set

From CORUM Protein Complexes

proteins in the Egfr-Grb2-mSos1 complex, EGF stimulated protein complex from the CORUM Protein Complexes dataset.

Lab-Grb2 complex, BCR stimulated Gene Set

From CORUM Protein Complexes

proteins in the Lab-Grb2 complex, BCR stimulated protein complex from the CORUM Protein Complexes dataset.

EGFR-CBL-GRB2 complex Gene Set

From CORUM Protein Complexes

proteins in the EGFR-CBL-GRB2 complex protein complex from the CORUM Protein Complexes dataset.

Grb2-Lab-Blnk complex, BCR stimulated Gene Set

From CORUM Protein Complexes

proteins in the Grb2-Lab-Blnk complex, BCR stimulated protein complex from the CORUM Protein Complexes dataset.

SLP-76-Cbl-Grb2-Shc complex, Fc receptor gamma-R1 stimulated Gene Set

From CORUM Protein Complexes

proteins in the SLP-76-Cbl-Grb2-Shc complex, Fc receptor gamma-R1 stimulated protein complex from the CORUM Protein Complexes dataset.

SHC-GRB2 complex Gene Set

From CORUM Protein Complexes

proteins in the SHC-GRB2 complex protein complex from the CORUM Protein Complexes dataset.

Shc-Ship-Grb2 complex, IL-3 stimulated Gene Set

From CORUM Protein Complexes

proteins in the Shc-Ship-Grb2 complex, IL-3 stimulated protein complex from the CORUM Protein Complexes dataset.

Grb2-mSos1 complex Gene Set

From CORUM Protein Complexes

proteins in the Grb2-mSos1 complex protein complex from the CORUM Protein Complexes dataset.

BCR-ABL (p210 fusion protein)-GRB2-SOS1 complex Gene Set

From CORUM Protein Complexes

proteins in the BCR-ABL (p210 fusion protein)-GRB2-SOS1 complex protein complex from the CORUM Protein Complexes dataset.

Grb2-Shp2 complex, FGF stimulated Gene Set

From CORUM Protein Complexes

proteins in the Grb2-Shp2 complex, FGF stimulated protein complex from the CORUM Protein Complexes dataset.

Grb2-Sos complex, Fc receptor gamma-R1 stimulated Gene Set

From CORUM Protein Complexes

proteins in the Grb2-Sos complex, Fc receptor gamma-R1 stimulated protein complex from the CORUM Protein Complexes dataset.

PLC-gamma-2-SLP-76-Lyn-Grb2 complex Gene Set

From CORUM Protein Complexes

proteins in the PLC-gamma-2-SLP-76-Lyn-Grb2 complex protein complex from the CORUM Protein Complexes dataset.

cRET-Shc-Grb2-Gab2-P85PI3K-Shp2 complex Gene Set

From CORUM Protein Complexes

proteins in the cRET-Shc-Grb2-Gab2-P85PI3K-Shp2 complex protein complex from the CORUM Protein Complexes dataset.

grb2ras Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term grb2ras in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

grb2gab1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term grb2gab1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

grb2sos Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term grb2sos in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

grb2mediated Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term grb2mediated in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

grb2sos1grb2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term grb2sos1grb2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

grb2sos1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term grb2sos1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

grb2sh2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term grb2sh2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

grb2associated Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term grb2associated in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

grb2-egfr complex Gene Set

From GO Cellular Component Annotations

proteins localized to the grb2-egfr complex cellular component from the curated GO Cellular Component Annotations dataset.

grb2-sos complex Gene Set

From GO Cellular Component Annotations

proteins localized to the grb2-sos complex cellular component from the curated GO Cellular Component Annotations dataset.

GRB2 events in EGFR signaling Gene Set

From Reactome Pathways

proteins participating in the GRB2 events in EGFR signaling pathway from the Reactome Pathways dataset.

GRB2 events in ERBB2 signaling Gene Set

From Reactome Pathways

proteins participating in the GRB2 events in ERBB2 signaling pathway from the Reactome Pathways dataset.

GRB2:SOS provides linkage to MAPK signaling for Integrins Gene Set

From Reactome Pathways

proteins participating in the GRB2:SOS provides linkage to MAPK signaling for Integrins pathway from the Reactome Pathways dataset.