guanylate cyclase 2D, membrane (retina-specific)

This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases. [provided by RefSeq, Dec 2008]

gucy2d Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term gucy2d in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

GUCY2D Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for GUCY2D from the Pathway Commons Protein-Protein Interactions dataset.