Name

HCRT Gene

hypocretin (orexin) neuropeptide precursor

This gene encodes a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B, which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2, function in the regulation of sleep and arousal. This neuropeptide arrangement may also play a role in feeding behavior, metabolism, and homeostasis. [provided by RefSeq, Jan 2010]

HCRTR2 Gene

hypocretin (orexin) receptor 2

The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein binds the hypothalamic neuropeptides orexin A and orexin B. A related gene (HCRTR1) encodes a G-protein coupled receptor that selectively binds orexin A. [provided by RefSeq, Jan 2009]

HCRTR1 Gene

hypocretin (orexin) receptor 1

The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B. [provided by RefSeq, Jan 2009]

HCRT Gene Set

From Guide to Pharmacology Protein Ligands of Receptors

receptors of the HCRT ligand (protein) from the curated Guide to Pharmacology Protein Ligands of Receptors dataset.

HCRT Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for HCRT from the Pathway Commons Protein-Protein Interactions dataset.

hcrtr1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term hcrtr1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

hcrtr2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term hcrtr2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

hcrt1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term hcrt1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

HCRTR1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for HCRTR1 from the Pathway Commons Protein-Protein Interactions dataset.

HCRTR2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for HCRTR2 from the Pathway Commons Protein-Protein Interactions dataset.