Name

HIRA Gene

histone cell cycle regulator

This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development. [provided by RefSeq, Jul 2008]

HIRAP1 Gene

histone cell cycle regulator pseudogene 1

hira Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term hira in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

HIRA Gene Set

From NURSA Protein-Protein Interactions

interacting proteins for HIRA from the NURSA Protein-Protein Interactions dataset.

HIRA Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for HIRA from the Pathway Commons Protein-Protein Interactions dataset.

hirahir Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term hirahir in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

hirano Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term hirano in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

hirahirbinding Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term hirahirbinding in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

HIRA B motif Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the HIRA B motif protein domain from the InterPro Predicted Protein Domain Annotations dataset.

HIRAN domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the HIRAN domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.