Name

HOMER3 Gene

homer scaffolding protein 3

This gene encodes a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors, inositol 1,4,5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation and trafficking of amyloid beta peptides. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009]

homer3 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term homer3 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

HOMER3 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for HOMER3 from the Pathway Commons Protein-Protein Interactions dataset.