HOXB5 Gene

homeobox B5

This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in lung and gut development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue. [provided by RefSeq, Jul 2008]

hoxb5 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term hoxb5 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

HoxB5 Gene Set

From MotifMap Predicted Transcription Factor Targets

target genes of the HoxB5 transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.

HOXB5 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for HOXB5 from the Pathway Commons Protein-Protein Interactions dataset.