Name

HPRT1 Gene

hypoxanthine phosphoribosyltransferase 1

The protein encoded by this gene is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway. Mutations in this gene result in Lesch-Nyhan syndrome or gout.[provided by RefSeq, Jun 2009]

HPRT1P1 Gene

hypoxanthine phosphoribosyltransferase 1 pseudogene 1

HPRT1P2 Gene

hypoxanthine phosphoribosyltransferase 1 pseudogene 2

HPRT1P3 Gene

hypoxanthine phosphoribosyltransferase 1 pseudogene 3

hprt1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term hprt1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

HPRT1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for HPRT1 from the Pathway Commons Protein-Protein Interactions dataset.