Name

ICAM5 Gene

intercellular adhesion molecule 5, telencephalin

The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases. [provided by RefSeq, Jul 2008]

icam5 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term icam5 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

ICAM5 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for ICAM5 from the Pathway Commons Protein-Protein Interactions dataset.