Name

IL11 Gene

interleukin 11

The protein encoded by this gene is a member of the gp130 family of cytokines. These cytokines drive the assembly of multisubunit receptor complexes, all of which contain at least one molecule of the transmembrane signaling receptor IL6ST (gp130). This cytokine is shown to stimulate the T-cell-dependent development of immunoglobulin-producing B cells. It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2012]

IL11RA Gene

interleukin 11 receptor, alpha

Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012]

il11 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term il11 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

IL11 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for IL11 from the Pathway Commons Protein-Protein Interactions dataset.

il11il11r Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term il11il11r in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

il11stat3 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term il11stat3 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

il11ra Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term il11ra in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

il11ralpha Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term il11ralpha in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

il11r Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term il11r in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

il11gp130stat3 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term il11gp130stat3 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

il11dependent Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term il11dependent in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

IL11RA Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for IL11RA from the Pathway Commons Protein-Protein Interactions dataset.