IL17RB Gene

interleukin 17 receptor B

The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor. [provided by RefSeq, Jul 2008]

il17rb Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term il17rb in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

IL17RB Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for IL17RB from the Pathway Commons Protein-Protein Interactions dataset.