Name

IL2RA Gene

interleukin 2 receptor, alpha

The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq, Nov 2009]

il2ra Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term il2ra in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

IL2RA Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for IL2RA from the Pathway Commons Protein-Protein Interactions dataset.

IL2-IL2RA-IL2RB complex Gene Set

From CORUM Protein Complexes

proteins in the IL2-IL2RA-IL2RB complex protein complex from the CORUM Protein Complexes dataset.

il2ralpha Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term il2ralpha in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.