Name

IL2RB Gene

interleukin 2 receptor, beta

The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. [provided by RefSeq, Jul 2008]

il2rb Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term il2rb in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

IL2RB Gene Set

From MSigDB Cancer Gene Co-expression Modules

co-expressed genes for IL2RB from the MSigDB Cancer Gene Co-expression Modules dataset.

IL2RB Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for IL2RB from the Pathway Commons Protein-Protein Interactions dataset.

IL2-IL2RA-IL2RB complex Gene Set

From CORUM Protein Complexes

proteins in the IL2-IL2RA-IL2RB complex protein complex from the CORUM Protein Complexes dataset.

il2rbeta Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term il2rbeta in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.