KLF12 Gene

Kruppel-like factor 12

Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. The protein encoded by this gene is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

KLF12 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for KLF12 from the Pathway Commons Protein-Protein Interactions dataset.

KLF12 Gene Set

From TRANSFAC Curated Transcription Factor Targets

target genes of the KLF12 transcription factor in low- or high-throughput transcription factor functional studies from the TRANSFAC Curated Transcription Factor Targets dataset.